Cradle: Engineer better proteins, faster

Cradle

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Type:
Website
Last Updated:
2025/08/17
Description:
Cradle leverages AI to generate protein candidates and improve their properties. Accelerate protein engineering with AI-driven protein design platform.
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AI protein design
protein engineering
machine learning
biotechnology
protein optimization

Overview of Cradle

Cradle: The AI-Powered Protein Engineering Platform

What is Cradle?

Cradle is an AI-driven protein design platform that empowers scientists to engineer better proteins, faster. By leveraging machine learning and experimental data, Cradle helps teams generate protein candidates and improve their properties, leading to more breakthroughs in fewer experiments.

How Cradle Works:

  1. Import Your Data: Upload wet lab data or define your goals and assays.
  2. Generate Candidates: Use AI to generate optimized candidates.
  3. Review Reports: Gain insights into candidate performance and expected outcomes.
  4. Validate in the Lab: Test candidates in your lab or with a CRO.
  5. Learn: Models learn from every round of wet lab data.
  6. Upload: Upload the new results.

Key Features:

  • AI-Powered Protein Design: Cradle's AI engine generates novel protein sequences with desired properties.
  • Multi-Property Optimization: Co-optimize multiple protein properties, such as activity, binding affinity, stability, and expression.
  • Data-Driven Learning: Cradle's models continuously learn from your experimental data, improving performance with each round.
  • Secure and Private: Your data remains private and secure, with full ownership of your intellectual property.
  • Customizable Predictors: Integrate internally developed predictors and visualize outputs within reports.

Why is Cradle important?

Cradle helps accelerate protein engineering by:

  • Reducing development timelines by 1.5-12x
  • Enabling the exploration of multiple design strategies
  • Compounding results across all properties
  • Optimizing proteins for various applications, including therapeutics, agriculture, and food ingredients

Who uses Cradle?

Leading scientific teams at companies like Novo Nordisk, Johnson & Johnson, and IFF trust Cradle to engineer proteins faster.

Where can I use Cradle?

Cradle is suitable for various protein engineering applications, including:

  • Antibody Engineering
  • Enzyme Engineering
  • Vaccine Development
  • Peptide Engineering

Cradle's AI platform can enhance the overall quality and efficiency of protein development, making it a valuable asset in the field of biotechnology.

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